Insights

Expert articles, thought leadership, AI in cardiology.

Evaluating NT-proBNP Thresholds and Referral Pathways in Heart Failure Diagnosis: A Comparative Analysis of NHS and EU Practices

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Illustration showing NT-proBNP thresholds in heart failure diagnosis compared between NHS and EU practices, with Cardio-HART report and blood samples.

NT-proBNP thresholds in heart failure diagnosis are essential for understanding how different healthcare systems identify and manage the disease. N-terminal pro B-type natriuretic peptide (NT-proBNP) is a key biomarker used in diagnosing heart failure (HF). However, the threshold levels that trigger referral and further testing vary significantly between healthcare systems, influencing both diagnostic accuracy and […]

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The Decision to Order NT-proBNP: How ECG Findings and Clinical Factors Influence Testing

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Laptop showing a Cardio-HART report with blood test tubes and a heart illustration – NT-proBNP and HFpEF diagnostic gaps in primary care.

Heart failure with preserved ejection fraction (HFpEF) is increasingly recognized as a common subtype of heart failure, particularly in older adults and women over the age of 65. Despite representing more than half of heart failure cases in this demographic, HFpEF is still underdiagnosed in primary care. A major reason lies in the limitations of

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NT-proBNP Testing in Heart Failure with Preserved Ejection Fraction (HFpEF): Diagnostic Challenges and Clinical Implications

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Laptop showing a Cardio-HART report with blood test tubes and a heart illustration, representing NT-proBNP testing and diagnostic gaps in HFpEF.

NT-proBNP in HFpEF diagnosis is increasingly recognized as a challenge, particularly among older women. Addressing these diagnostic challenges is critical because HFpEF now represents more than half of all heart failure cases in older adults, and timely recognition can substantially reduce hospital admissions. Despite its growing significance, HFpEF remains frequently underdiagnosed in primary care due

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The Impact of Obesity on NT-proBNP in Heart Failure: Focus on HFpEF and Early Diagnosis

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NT-proBNP in Heart Failure: obesity complicates diagnosis and HFpEF detection with Cardio-HART support

Key takeaways (TL;DR): NT-proBNP in Heart Failure is central to diagnosis, but obesity complicates interpretation. Obesity has emerged as a significant health challenge, particularly as the aging population in the UK continues to grow. With one in four adults in the UK classified as obese, this condition is becoming one of the leading contributors to

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NT-proBNP and Diabetes: Risks of Misdiagnosis in Heart Failure

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NT-proBNP and diabetes — heart illustration, blood vials, and a laptop displaying a Cardio-HART report, illustrating heart-failure diagnosis in diabetic patients

NT-proBNP and diabetes are closely linked, and this interplay can alter test interpretation in heart-failure diagnosis. N-terminal pro B-type natriuretic peptide (NT-proBNP) is a biomarker widely used to assess heart failure (HF) and other cardiovascular conditions. It is the inactive fragment released when the heart produces brain natriuretic peptide (BNP), a hormone involved in fluid

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NT-proBNP in Heart Failure Diagnosis: Clinical Delay, Biomarker Limits, and the Need for Diagnostic Reinvention

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  Misconceptions, Misuse, and Missed Diagnoses in the Primary Care Pathway. Abstract – Misuse of NT-proBNP in Primary Care and Diagnostic Delays N-terminal pro B-type natriuretic peptide (NT-proBNP) is widely used in the diagnostic pathway for heart failure (HF). While it remains a sensitive marker for excluding HF, particularly in acute settings, its application in

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NT-proBNP in Heart Failure Diagnosis: Challenges, Clinical Effectiveness, and the Need for More Accurate Tools

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Abstract N-terminal pro B-type natriuretic peptide (NT-proBNP) has long been used as a biomarker for diagnosing heart failure (HF), especially in emergency settings. However, its clinical effectiveness in diagnosing heart failure with preserved ejection fraction (HFpEF), particularly in older adults, remains a subject of debate due to high false-positive (FP) rates and evolving diagnostic criteria.

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Cardio-HART and QTc

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CHART and QTc Introduction The Cardio-HART (CHART) system assesses the QT interval as part of a comprehensive 12-lead ECG interpretation. CHART is specifically designed to provide a detailed evaluation of QT interval severity. This includes distinguishing between borderline cases and cases with prolonged or shortened QTc, with additional support provided through multiple QTc measurements. The

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Prevention in Cardiology: The Power of Community Support with Cardio-HART

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Preventive care is crucial in the field of cardiology. Recognizing the importance of early detection and proactive care, Cardio Phoenix has developed Cardio-HART—a groundbreaking solution for the early detection of cardiovascular diseases. As Cardio Phoenix applies for NIHR i4i funding to further its research, it becomes increasingly crucial to emphasize the significance of community support

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Telemedicine for the heart post COVID-19 / Sportello Cuore – Italy

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The research develops systems that bring general practitioners and specialists together to identify and monitor those at risk. The great challenge to SARS-CoV-2 virus infection is played out on the ground, through the early identification of new infections and the identification of those at greater risk, such as people with confirmed cardiovascular diseases or risk

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